Associate Professor
UConn Health
Farmington, Connecticut, United States
Lisa Mehlmann
Associate Professor of Cell Biology, UConn Health
My research interests are centered on female reproductive biology, in particular on the signaling events within oocytes that regulate oocyte maturation and fertilization. As a graduate student, I studied the development of Ca2+ release mechanisms during mouse oocyte maturation, work that has been followed up in my lab using human oocytes. As a postdoc, I identified the Gαs-coupled receptor, GPR3, that is critical for maintaining meiotic arrest at prophase prior to the preovulatory surge in luteinizing hormone that re-starts the meiotic cell cycle and determined that this receptor likely functions in human oocytes, as well. Most recently, my research has focused on the reproductive consequences of administering androgens to female mice. These mice serve as a useful model for transgender males – individuals assigned female at birth based on anatomy but who identify as male and take testosterone to achieve male characteristics.
Relevant publications:
Bartels, C.B., Uliasz, T.F., Lestz, L., and Mehlmann, L.M. 2021. Short-term testosterone use in female mice does not impair fertilizability of eggs: Implications for the fertility care of transgender males. Hum. Reprod. 36:189-198.
Godiwala, P., Uliasz, T.F., Lowther, K.M., Kaback, D., and Mehlmann, L.M. 2023. Puberty suppression followed by testosterone therapy does not impair reproductive potential in female mice. Endocrinology 164:1–10.
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Wednesday, July 30, 2025
10:30 AM - 11:00 AM EDT