Professor
Division of Germ Cell Biology, National Institute for Basic Biology
Okazaki, Aichi, Japan
Shosei Yoshida is a Professor in the Division of Germ Cell Biology at the National Institute for Basic Biology (NIBB), Japan. He graduated from the University of Tokyo with an MD in 1991 and earned his PhD in 1995. Shosei began his research on germ cells as a non-independent assistant professor at Osaka University in 1996, later moving to Kyoto University, before establishing his own laboratory at NIBB in 2008. Using the mouse as a model, his research focuses on the cellular identity and fate dynamics of spermatogenic stem cells (SSCs), and their spatiotemporal regulation within the testis. To this end, he has developed live-imaging and fate-tracing technologies using pulse-labeled cells, combined with mathematical modeling. His key discoveries include the reversible potential of differentiation-primed SSCs to return to the self-renewing pool, active SSC migration among differentiating progeny within a vasculature-associated open niche, and SSC density homeostasis maintained through competition for mitogens.
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Dynamic SSC Regulation Self-Organizes the Spermatogenic Cycle and Wave
Friday, August 1, 2025
10:30 AM - 11:00 AM EDT