Professor
The University of Texas at San Antonio
San Antonio, Texas, United States
Dr. Hermann received his PhD in 2005 from the University of Kansas Medical Center under the supervision of Leslie Heckert where he studied transcriptional regulation of the FSH-receptor and Steroidogenic Factor-1 genes. He then completed postdoctoral training in lab of Dr. Kyle Orwig at the Magee-Womens Research Institute, University of Pittsburgh where he performed the first definitive spermatogonial stem cell (SSC) transplantation in non-human primates. With support from an NIH K99/R00 award, Dr. Hermann started his lab at the University of Texas at San Antonio (UTSA) in 2011. The Hermann lab studies the mechanisms regulating SSCs fate specification during testicular development, SSC fate in adults during steady-state spermatogenesis, and potential SSC-based therapeutic strategies for male infertility. Dr. Hermann also founded the UTSA Genomics Core, which specializes in single-cell and spatial methodologies, and has applied those approaches to understanding the identity of SSCs and their regulatory framework. More recently, his lab has collaborated on development of male germline-based technologies for non-human primate transgenesis and non-hormonal male contraceptives targeting proteins expressed in spermatogonia.
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Development of RBM46 Small Molecular Degraders for Reversible Male Contraception
Wednesday, July 30, 2025
1:30 PM - 2:00 PM EDT