IVF Coordinator Reproductive Fertility Center LOS ANGELES, United States
Abstract Authors: Grace Pouri¹, Sharlene Saadat¹, Audrey Golding¹, Allen P. Chen², Peyman Saadat¹
Abstract Text: The Effect of Hysteroscopy on Pregnancy Rates Before Frozen Embryo Transfer with PGT- Tested Embryos in a Highly Selected Group of Surrogates G. Pouri1, S. Saadat1, A. Golding1, A. P. Chen2, P. Saadat1 1. Reproductive Fertility, USA, West Hollywood, California 2. Miracle Conception, LLC, USA, Los Angeles, California Assessing the value of performing a hysteroscopy prior to a frozen embryo transfer (FET) on implantation and clinical pregnancy rates has yielded varying results in previous studies. This study aimed to determine whether performing a hysteroscopy prior to FET improves implantation and clinical pregnancy outcomes on a highly selected group of surrogates using PGT-tested embryos. We hypothesized that a pre-transfer hysteroscopy would increase implantation and pregnancy rates. To test this hypothesis, we used the following methods:
Identified 124 surrogates who underwent FET and divided them into 2 groups: one group of 32 who had undergone a hysteroscopy procedure prior to FET, and the second group of 92 surrogates who did not undergo a hysteroscopy procedure prior to FET.
Evaluated implantation and clinical pregnancy success based on beta HCG results 9 and 11 days after the FET. Clinical pregnancy was confirmed via ultrasound 4 weeks after the FET, when a heartbeat was detected in the growing fetus.
Only genetically PGT tested normal embryos were included in this study.
Our findings demonstrated an increase in implantation and clinical pregnancy rates among patients who underwent hysteroscopy before embryo transfer (p < 0.05). Specifically, the positive beta HCG results were 90% and clinical pregnancy rates were 87% in the hysteroscopy group. For those who did not have a hysteroscopy prior to FET, the positive beta HCG results were 82%, but the clinical pregnancy rate was 70%. These results suggest that hysteroscopy before FET may enhance implantation and clinical pregnancy rates. Our data indicates the likelihood of a successful implantation and clinical pregnancy improves in patients who undergo hysteroscopy before a frozen embryo transfer, compared to those who don’t have the hysteroscopy procedure.
